Ito, Kousei: search on Z-Library

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1

Establishment of a Drug-Induced, Bile Acid–Dependent Hepatotoxicity Model Using HepaRG Cells

Susukida, Takeshi, Sekine, Shuichi, Nozaki, Mayuka, Tokizono, Mayuko, Oizumi, Kumiko, Horie, Toshiharu, Ito, Kousei

Journal:

Journal of Pharmaceutical Sciences

Year:

2016

Language:

english

File:

PDF, 1.72 MB

english, 2016

2

ABCG2 is a High-Capacity Urate Transporter and its Genetic Impairment Increases Serum Uric Acid Levels in Humans

Nakayama, Akiyoshi, Matsuo, Hirotaka, Takada, Tappei, Ichida, Kimiyoshi, Nakamura, Takahiro, Ikebuchi, Yuki, Ito, Kousei, Hosoya, Tatsuo, Kanai, Yoshikatsu, Suzuki, Hiroshi, Shinomiya, Nariyoshi

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2011

Language:

english

File:

PDF, 201 KB

english, 2011

3

4.0-inch Active-Matrix Organic Light-Emitting Diode Display Integrated with Driver Circuits Using Amorphous In–Ga–Zn-Oxide Thin-Film Transistors with Suppressed Variation

Ohara, Hiroki, Sasaki, Toshinari, Noda, Kousei, Ito, Shunichi, Sasaki, Miyuki, Endo, Yuta, Yoshitomi, Shuhei, Sakata, Junichiro, Serikawa, Tadashi, Yamazaki, Shunpei

Journal:

Japanese Journal of Applied Physics

Year:

2010

Language:

english

File:

PDF, 142 KB

english, 2010

4

Metabolic Activation of Cholestatic Drug-induced Bile Acid-dependent Toxicity in Human Sandwich-Cultured Hepatocytes

Ogimura, Eiichiro, Tokizono, Mayuko, Sekine, Shuichi, Nakagawa, Tetsuya, Bando, Kiyoko, Ito, Kousei

Journal:

Journal of Pharmaceutical Sciences

Year:

2017

Language:

english

File:

PDF, 538 KB

english, 2017

5

Oxidative stress and enhanced paracellular permeability in the small intestine of methotrexate-treated rats

Tomoko Maeda, Yuko Miyazono, Kousei Ito, Kazuma Hamada, Shuichi Sekine, Toshiharu Horie

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2010

Language:

english

File:

PDF, 354 KB

english, 2010

6

Female type 2 diabetes mellitus mice exhibit severe ischemic brain damage

Akiko Sakata, Masaki Mogi, Jun Iwanami, Kana Tsukuda, Li-Juan Min, Fei Jing, Kousei Ohshima, Masaharu Ito, Masatsugu Horiuchi

Journal:

Journal of the American Society of Hypertension

Year:

2011

Language:

english

File:

PDF, 503 KB

english, 2011

7

Involvement of Organic Cation Transporters in the Clearance and Milk Secretion of Thiamine in Mice

Kato, Koji, Moriyama, Chihiro, Ito, Naoki, Zhang, Xuan, Hachiuma, Kenji, Hagima, Naoko, Iwata, Katsuya, Yamaguchi, Jun-ichi, Maeda, Kazuya, Ito, Kousei, Suzuki, Hiroshi, Sugiyama, Yuichi, Kusuhara, Hi

Journal:

Pharmaceutical Research

Year:

2015

Language:

english

File:

PDF, 1.15 MB

english, 2015

8

Fluorescein-methotrexate transport in brush border membrane vesicles from rat small intestine

Tiesong Li, Takashi Tomimatsu, Kousei Ito, Toshiharu Horie

Journal:

Year:

2003

Language:

english

File:

PDF, 133 KB

english, 2003

9

Quantitative assessment of the effects of sulfamethoxazole on Toxoplasma gondii loads in susceptible WT C57BL/6 mice as an immunocompetent host model

Belal, Usama S., Norose, Kazumi, Mohamed, Rabie M., Sekine, Shuichi, Nukaga, Takumi, Ito, Kousei, Abdellatif, Manal Z., Abdelgelil, Noha H., Yano, Akihiko

Journal:

Parasitology International

Year:

2016

Language:

english

File:

PDF, 368 KB

english, 2016

10

Detection of Abacavir-Induced Structural Alterations in Human Leukocyte Antigen-B*57â:â01 Using Phage Display

Shirayanagi, Tomohiro, Aoki, Shigeki, Fujimori, Sota, Watanabe, Kenji, Aida, Tetsuo, Hirasawa, Makoto, Kumagai, Kazuyoshi, Hoshino, Tyuji, Ito, Kousei

Journal:

Biological & Pharmaceutical Bulletin

Year:

2020

File:

PDF, 1.28 MB

2020

11

Ethacrynic-acid-induced glutathione depletion and oxidative stress in normal and Mrp2-deficient rat liver

Bin Ji, Kousei Ito, Shuichi Sekine, Ai Tajima, Toshiharu Horie

Journal:

Free Radical Biology and Medicine

Year:

2004

Language:

english

File:

PDF, 572 KB

english, 2004

12

Receptor for activated C-kinase 1 regulates the cellular localization and function of ABCB4

Yuki Ikebuchi, Tappei Takada, Kousei Ito, Takashi Yoshikado, Naohiko Anzai, Yoshikatsu Kanai, Hiroshi Suzuki

Journal:

Hepatology Research

Year:

2009

Language:

english

File:

PDF, 605 KB

english, 2009

13

Heart rate-dependent alteration of the frequency and coupling interval of ventricular arrhythmias as measured by 24-hour ECG monitoring.

INOUE, TOSHIO, KOUMATSU, KOUSEI, ITO, MORIO, ARITA, MAKOTO, SAIKAWA, TETSUNORI

Journal:

Japanese Circulation Journal

Year:

1991

File:

PDF, 994 KB

1991

14

Prediction of the potential risk of idiosyncratic drug toxicity

Ito, Kousei, Kobayashi, Kaoru

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2017

Language:

english

File:

PDF, 131 KB

english, 2017

15

cDNA cloning of a new member of the FTZ-F1 subfamily from a rainbow trout

Michihiko Ito, Aki Masuda, Kousei Yumoto, Asako Otomo, Yusuke Takahashi, Nobuhiko Takamatsu, Hiromi Kanda, Shinya Yamashita, Tadayoshi Shiba

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1998

Language:

english

File:

PDF, 373 KB

english, 1998

16

Metabolic activation of hepatotoxic drug (benzbromarone) induced mitochondrial membrane permeability transition

Shirakawa, Maho, Sekine, Shuichi, Tanaka, Ayaka, Horie, Toshiharu, Ito, Kousei

Journal:

Toxicology and Applied Pharmacology

Year:

2015

Language:

english

File:

PDF, 748 KB

english, 2015

17

Differential Diagnosis of Pancreatic Epidermoid Cyst Without a Solid Component (Residual Splenic Tissue) vs. Mucinous Cystic Neoplasm

Ishigami, Kousei, Nishie, Akihiro, Irie, Hiroyuki, Asayama, Yoshiki, Ushijima, Yasuhiro, Takayama, Yukihisa, Okamoto, Daisule, Fujita, Nobuhiro, Ohtsuka, Takao, Ito, Tetsuhide, Mochidome, Naoki, Honda

Journal:

Journal of Gastrointestinal Cancer

Year:

2017

Language:

english

File:

PDF, 5.74 MB

english, 2017

18

The prevalence of circumportal pancreas as shown by multidetector-row computed tomography

Kousei Ishigami, Tsuyoshi Tajima, Akihiro Nishie, Yoshiki Asayama, Daisuke Kakihara, Tomohiro Nakayama, Ken Shirabe, Akinobu Taketomi, Masafumi Nakamura, Shunichi Takahata, Tetsuhide Ito, Hiroshi Hond

Journal:

Insights into Imaging

Year:

2011

Language:

english

File:

PDF, 525 KB

english, 2011

19

Differential diagnosis of groove pancreatic carcinomas vs. groove pancreatitis: Usefulness of the portal venous phase

Kousei Ishigami, Tsuyoshi Tajima, Akihiro Nishie, Daisuke Kakihara, Nobuhiro Fujita, Yoshiki Asayama, Yasuhiro Ushijima, Hiroyuki Irie, Masafumi Nakamura, Shunichi Takahata, Tetsuhide Ito, Hiroshi Hon

Journal:

European Journal of Radiology

Year:

2010

Language:

english

File:

PDF, 1013 KB

english, 2010

20

Characterization of bile acid transport mediated by multidrug resistance associated protein 2 and bile salt export pump

Hidetaka Akita, Hiroshi Suzuki, Kousei Ito, Setsuo Kinoshita, Norihito Sato, Hajime Takikawa, Yuichi Sugiyama

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2001

Language:

english

File:

PDF, 414 KB

english, 2001

21

21.3: 4.0 In. QVGA AMOLED Display Using In-Ga-Zn-Oxide TFTs with a Novel Passivation Layer

Ohara, Hiroki, Sasaki, Toshinari, Noda, Kousei, Ito, Shunichi, Sasaki, Miyuki, Toyosumi, Yayoi, Endo, Yuta, Yoshitomi, Shuhei, Sakata, Junichiro, Serikawa, Tadashi, Yamazaki, Shunpei

Journal:

SID Symposium Digest of Technical Papers

Year:

2009

Language:

english

File:

PDF, 630 KB

english, 2009

22

Basal efflux of bile acids contributes to drug-induced bile acid-dependent hepatocyte toxicity in rat sandwich-cultured hepatocytes

Susukida, Takeshi, Sekine, Shuichi, Ogimura, Eiichiro, Aoki, Shigeki, Oizumi, Kumiko, Horie, Toshiharu, Ito, Kousei

Journal:

Toxicology in Vitro

Year:

2015

Language:

english

File:

PDF, 1.21 MB

english, 2015

23

ABCC2/Abcc2 Transport Property in Different Species and its Modulation by Heterogeneous Factors

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2008

Language:

english

File:

PDF, 1023 KB

english, 2008

24

Identification of bile acids responsible for inhibiting the bile salt export pump, leading to bile acid accumulation and cell toxicity in rat hepatocytes

Oizumi, Kumiko, Sekine, Shuichi, Fukagai, Meiko, Susukida, Takeshi, Ito, Kousei

Journal:

Journal of Pharmaceutical Sciences

Year:

2017

Language:

english

File:

PDF, 4.71 MB

english, 2017

25

Predictive Factors for the Metachronous Development of High-risk Lesions in the Remnant Pancreas After Partial Pancreatectomy for Intraductal Papillary Mucinous Neoplasm

Miyasaka, Yoshihiro, Ohtsuka, Takao, Tamura, Koji, Mori, Yasuhisa, Shindo, Koji, Yamada, Daisuke, Takahata, Shunichi, Ishigami, Kousei, Ito, Tetsuhide, Tokunaga, Shoji, Oda, Yoshinao, Mizumoto, Kazuhi

Journal:

Annals of Surgery

Year:

2016

Language:

english

File:

PDF, 307 KB

english, 2016

26

Cumulative effects of heart beat on ventricular premature contractions suggesting possible involvement of triggered activity.

KOUMATSU, KOUSEI, ITO, MORIO, FUJINO, TAKAO, SAIKAWA, TETSUNORI, ARITA, MAKOTO

Journal:

Japanese Circulation Journal

Year:

1993

File:

PDF, 1.01 MB

1993

27

Adenocarcinoma Involving the Whole Pancreas with Multiple Pancreatic Masses

Fujimori, Nao, Nakamura, Taichi, Oono, Takamasa, Igarashi, Hisato, Takahata, Shunichi, Nakamura, Masafumi, Tanaka, Masao, Hayashi, Akifumi, Aishima, Shinichi, Ishigami, Kousei, Ogoshi, Keiichiro, Ito,

Journal:

Internal Medicine

Year:

2010

Language:

english

File:

PDF, 1.72 MB

english, 2010

28

Expression of a putative ATP-binding cassette region, homologous to that in multidrug resistance-associated protein (MRP), is hereditarily defective in Eisai hyperbilirubinemic rats (EHBR)

Kousei Ito, Hiroshi Suzuki, Tomoko Hirohashi, Kazuhiko Kume, Takao Shimizu, Yuichi Sugiyama

Journal:

International Hepatology Communications

Year:

1996

Language:

english

File:

PDF, 549 KB

english, 1996

29

Assessment of mitochondrial dysfunction-related, drug-induced hepatotoxicity in primary rat hepatocytes

Liu, Cong, Sekine, Shuichi, Ito, Kousei

Journal:

Toxicology and Applied Pharmacology

Year:

2016

Language:

english

File:

PDF, 676 KB

english, 2016

30

Troglitazone inhibits bile acid amidation: a possible risk factor for liver injury

Ogimura, Eiichiro, Nakagawa, Tetsuya, Deguchi, Jiro, Sekine, Shuichi, Ito, Kousei, Bando, Kiyoko

Journal:

Toxicological Sciences

Year:

2017

Language:

english

File:

PDF, 1.00 MB

english, 2017

31

Ursodeoxycholic acid stimulates the formation of the bile canalicular network

Yuki Ikebuchi, Hidetoshi Shimizu, Kousei Ito, Takashi Yoshikado, Yoshihide Yamanashi, Tappei Takada, Hiroshi Suzuki

Journal:

Biochemical Pharmacology

Year:

2012

Language:

english

File:

PDF, 2.18 MB

english, 2012

32

Contribution of Protein Binding, Lipid Partitioning, and Asymmetrical Transport to Drug Transfer into Milk in MouseVersusHuman

Ito, Naoki, Ito, Kousei, Koshimichi, Hiroki, Hisaka, Akihiro, Honma, Masashi, Igarashi, Takashi, Suzuki, Hiroshi

Journal:

Pharmaceutical Research

Year:

2013

Language:

english

File:

PDF, 361 KB

english, 2013

33

Evaluation of the performance of deformable image registration between planning CT and CBCT images for the pelvic region: comparison between hybrid and intensity-based DIR

TAKAYAMA, Yoshiki, KADOYA, Noriyuki, YAMAMOTO, Takaya, ITO, Kengo, CHIBA, Mizuki, FUJIWARA, Kousei, MIYASAKA, Yuya, DOBASHI, Suguru, SATO, Kiyokazu, TAKEDA, Ken, JINGU, Keiichi

Journal:

Journal of Radiation Research

Year:

2017

Language:

english

File:

PDF, 387 KB

english, 2017

34

Intravoxel incoherent motion magnetic resonance imaging for assessment of chronic pancreatitis with special focus on its early stage

Fujita, Nobuhiro, Nishie, Akihiro, Asayama, Yoshiki, Ishigami, Kousei, Fujimori, Nao, Ito, Tetsuhide, Honda, Hiroshi

Journal:

Acta Radiologica

Year:

2019

Language:

english

File:

PDF, 781 KB

english, 2019

35

An animal model of abacavir-induced HLA-mediated liver injury

Song, Binbin, Aoki, Shigeki, Liu, Cong, Susukida, Takeshi, Ito, Kousei

Journal:

Toxicological Sciences

Year:

2018

Language:

english

File:

PDF, 1.79 MB

english, 2018

36

In vitro bile acid-dependent hepatocyte toxicity assay system using human induced pluripotent stem cell-derived hepatocytes: Current status and disadvantages to overcome

Sakai, Yoko, Iwao, Takahiro, Susukida, Takeshi, Nukaga, Takumi, Takemura, Akinori, Sekine, Shuichi, Ito, Kousei, Matsunaga, Tamihide

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2019

Language:

english

File:

PDF, 1.04 MB

english, 2019

37

Key determinants of the circulatory exposure of organic anions: differences in hepatic uptake between multidrug resistance-associated protein 2 (Mrp2)-deficient rats and wild-type rats

Kosaka, Keigo, Watanabe, Tomoko, Susukida, Takeshi, Aoki, Shigeki, Sekine, Shuichi, Kume, Toshiyuki, Ito, Kousei

Journal:

Year:

2015

Language:

english

File:

PDF, 878 KB

english, 2015

38

Aged Garlic Extract Protects against Methotrexate-Induced Apoptotic Cell Injury of IEC-6 Cells

Horie, Toshiharu, Li, Tiesong, Ito, Kousei, Sumi, Shin-ichiro, Fuwa, Toru

Journal:

Journal of Nutrition

Year:

2006

Language:

english

File:

PDF, 101 KB

english, 2006

39

Single amino acid substitution of rat MRP2 results in acquired transport activity for taurocholate

Ito, Kousei, Suzuki, Hiroshi, Sugiyama, Yuichi

Journal:

American Journal of Physiology - Gastrointestinal and Liver Physiology

Year:

2001

Language:

english

File:

PDF, 351 KB

english, 2001

40

A toll-like receptor 9 agonist sensitizes mice to mitochondrial dysfunction-induced hepatic apoptosis via the Fas/FasL pathway

Song, Binbin, Aoki, Shigeki, Liu, Cong, Ito, Kousei

Journal:

Archives of Toxicology

Year:

2019

Language:

english

File:

PDF, 6.80 MB

english, 2019

41

HLA transgenic mice: application in reproducing idiosyncratic drug toxicity

Susukida, Takeshi, Aoki, Shigeki, Shirayanagi, Tomohiro, Yamada, Yushiro, Kuwahara, Saki, Ito, Kousei

Journal:

Drug Metabolism Reviews

Year:

2020

File:

PDF, 2.31 MB

2020

42

Oxidative stress and Mrp2 internalization

Shuichi Sekine, Kousei Ito, Toshiharu Horie

Journal:

Free Radical Biology and Medicine

Year:

2006

Language:

english

File:

PDF, 368 KB

english, 2006

43

Transport of fluorescein methotrexate by multidrug resistance-associated protein 3 in IEC-6 cells

Li, Tiesong, Ito, Kousei, Horie, Toshiharu

Journal:

American Journal of Physiology - Gastrointestinal and Liver Physiology

Year:

2003

Language:

english

File:

PDF, 297 KB

english, 2003

44

An increase in the number of predictive factors augments the likelihood of malignancy in branch duct intraductal papillary mucinous neoplasm of the pancreas

Takao Ohtsuka, Hiroshi Kono, Yosuke Nagayoshi, Yasuhisa Mori, Kosuke Tsutsumi, Yoshihiko Sadakari, Shunichi Takahata, Katsuya Morimatsu, Shinichi Aishima, Hisato Igarashi, Tetsuhide Ito, Kousei Ishiga

Journal:

Year:

2012

Language:

english

File:

PDF, 175 KB

english, 2012

45

MRI findings of pancreatic lymphoma and autoimmune pancreatitis: A comparative study

Kousei Ishigami, Tsuyoshi Tajima, Akihiro Nishie, Yasuhiro Ushijima, Nobuhiro Fujita, Yoshiki Asayama, Daisuke Kakihara, Hiroyuki Irie, Tetsuhide Ito, Hisato Igarashi, Masafumi Nakamura, Hiroshi Honda

Journal:

European Journal of Radiology

Year:

2010

Language:

english

File:

PDF, 1.20 MB

english, 2010

46

Autophagy is an important metabolic pathway to determine leukemia cell survival following suppression of the glycolytic pathway

Kawaguchi, Moemi, Aoki, Shigeki, Hirao, Takuya, Morita, Michie, Ito, Kousei

Journal:

Biochemical and Biophysical Research Communications

Year:

2016

Language:

english

File:

PDF, 547 KB

english, 2016

47

Evaluation of immune-mediated idiosyncratic drug toxicity using chimeric HLA transgenic mice

Susukida, Takeshi, Aoki, Shigeki, Kogo, Kotaro, Fujimori, Sota, Song, Binbin, Liu, Cong, Sekine, Shuichi, Ito, Kousei

Journal:

Archives of Toxicology

Year:

2017

Language:

english

File:

PDF, 4.66 MB

english, 2017

48

Altered intracellular signaling by imatinib increases the anti-cancer effects of tyrosine kinase inhibitors in chronic myelogenous leukemia cells

Hirao, Takuya, Yamaguchi, Masashi, Kikuya, Megumi, Chibana, Hiroji, Ito, Kousei, Aoki, Shigeki

Journal:

Year:

2017

Language:

english

File:

PDF, 1.31 MB

english, 2017

49

Sustained intrahepatic glutathione depletion causes proteasomal degradation of multidrug resistance-associated protein 2 in rat liver

Shuichi Sekine, Kaori Mitsuki, Kousei Ito, Satoe Kugioka, Toshiharu Horie

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2012

Language:

english

File:

PDF, 792 KB

english, 2012

50

Multidrug Resistance-Associated Protein 2 (MRP2) Enhances 4-Hydroxynonenal-Induced Toxicity in Madin−Darby Canine Kidney II Cells

Ji, Bin, Ito, Kousei, Horie, Toshiharu

Journal:

Chemical Research in Toxicology

Year:

2004

Language:

english

File:

PDF, 481 KB

english, 2004

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